Overcoming chemotherapy resistance using pH-sensitive hollow MnO(2) nanoshells that target the hypoxic tumor microenvironment of metastasized oral squamous cell carcinoma

BACKGROUND: Smart nanoscale drug delivery systems that target acidic tumor microenvironments (TME) could offer controlled release of drugs and modulate the hypoxic TME to enhance cancer therapy. The majority of previously reported MnO(2) nanostructures are nanoparticles, nanosheets, or nanocomposite...

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Detalhes bibliográficos
Publicado no:J Nanobiotechnology
Main Authors: Zhou, Zhi-hang, Liang, Si-yuan, Zhao, Tong-chao, Chen, Xu-zhuo, Cao, Xian-kun, Qi, Ming, Huang, Ying-ying, Ju, Wu-tong, Yang, Meng, Zhu, Dong-wang, Pang, Yi-chuan, Zhong, Lai-ping
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2021
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8157461/
https://ncbi.nlm.nih.gov/pubmed/34039370
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12951-021-00901-9
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