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Living-Cell Diffracted X-ray Tracking Analysis Confirmed Internal Salt Bridge Is Critical for Ligand-Induced Twisting Motion of Serotonin Receptors
Serotonin receptors play important roles in neuronal excitation, emotion, platelet aggregation, and vasoconstriction. The serotonin receptor subtype 2A (5-HT(2A)R) is a Gq-coupled GPCR, which activate phospholipase C. Although the structures and functions of 5-HT(2A)Rs have been well studied, little...
Tallennettuna:
| Julkaisussa: | Int J Mol Sci |
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| Päätekijät: | , , , , , , |
| Aineistotyyppi: | Artigo |
| Kieli: | Inglês |
| Julkaistu: |
MDPI
2021
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| Aiheet: | |
| Linkit: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8157010/ https://ncbi.nlm.nih.gov/pubmed/34067933 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms22105285 |
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