Antitumor Activity of Nitazoxanide against Colon Cancers: Molecular Docking and Experimental Studies Based on Wnt/β-Catenin Signaling Inhibition

In colon cancer, wingless (Wnt)/β-catenin signaling is frequently upregulated; however, the creation of a molecular therapeutic agent targeting this pathway is still under investigation. This research aimed to study how nitazoxanide can affect Wnt/β-catenin signaling in colon cancer cells (HCT-116)...

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Bibliografiset tiedot
Julkaisussa:Int J Mol Sci
Päätekijät: Abd El-Fadeal, Noha M., Nafie, Mohamed S., K. El-kherbetawy, Mohammed, El-mistekawy, Amr, Mohammad, Hala M. F., Elbahaie, Alaaeldeen M., Hashish, Abdullah A., Alomar, Suliman Y., Aloyouni, Sheka Yagub, El-dosoky, Mohamed, Morsy, Khaled M., Zaitone, Sawsan A.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: MDPI 2021
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Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC8156814/
https://ncbi.nlm.nih.gov/pubmed/34069111
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms22105213
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