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Sustained Release of Bone Morphogenetic Protein-2 through Alginate Microbeads Enhances Bone Regeneration in Rabbit Tibial Metaphyseal Defect Model

Bone morphogenetic protein-2 (BMP-2) is widely used to enhance bone regeneration. However, because of its short half-life and rapid disappearance, large amounts of BMP-2 are needed, leading to unintended side effects. In this study, BMP-2-encapsulated alginate microbeads (AM) were used to enhance bo...

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Detalhes bibliográficos
Publicado no:Materials (Basel)
Main Authors: Kim, Junhyung, Lee, Seoyun, Choi, Yonghyun, Choi, Jonghoon, Kang, Byung-Jae
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8156783/
https://ncbi.nlm.nih.gov/pubmed/34067593
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ma14102600
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