Treatment with an Anti-CX3CL1 Antibody Suppresses M1 Macrophage Infiltration in Interstitial Lung Disease in SKG Mice

CX3C Motif Chemokine Ligand 1 (CX3CL1; fractalkine) has been implicated in the pathogenesis of rheumatoid arthritis (RA) and its inhibition was found to attenuate arthritis in mice as well as in a clinical trial. Therefore, we investigated the effects of an anti-CX3CL1 monoclonal antibody (mAb) on i...

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Vydáno v:Pharmaceuticals (Basel)
Hlavní autoři: Mizutani, Satoshi, Nishio, Junko, Kondo, Kanoh, Motomura, Kaori, Yamada, Zento, Masuoka, Shotaro, Yamada, Soichi, Muraoka, Sei, Ishii, Naoto, Kuboi, Yoshikazu, Sendo, Sho, Mikami, Tetuo, Imai, Toshio, Nanki, Toshihiro
Médium: Artigo
Jazyk:Inglês
Vydáno: MDPI 2021
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC8156344/
https://ncbi.nlm.nih.gov/pubmed/34067842
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ph14050474
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