Acute acetate administration increases endogenous opioid levels in the human brain: A [(11)C]carfentanil molecular imaging study

INTRODUCTION: A recent study has shown that acetate administration leads to a fourfold increase in the transcription of proopiomelanocortin (POMC) mRNA in the hypothalamus. POMC is cleaved to peptides, including β-endorphin, an endogenous opioid (EO) agonist that binds preferentially to the µ-opioid...

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Опубликовано в: :J Psychopharmacol
Главные авторы: Ashok, Abhishekh H, Myers, Jim, Frost, Gary, Turton, Samuel, Gunn, Roger N, Passchier, Jan, Colasanti, Alessandro, Marques, Tiago Reis, Nutt, David, Lingford-Hughes, Anne, Howes, Oliver D, Rabiner, Eugenii A
Формат: Artigo
Язык:Inglês
Опубликовано: SAGE Publications 2021
Предметы:
Short Reports
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC8155733/
https://ncbi.nlm.nih.gov/pubmed/33406950
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/0269881120965912
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