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Reduced mu opioid receptor availability in schizophrenia revealed with [(11)C]-carfentanil positron emission tomographic Imaging

Negative symptoms, such as amotivation and anhedonia, are a major cause of functional impairment in schizophrenia. There are currently no licensed treatments for negative symptoms, highlighting the need to understand the molecular mechanisms underlying them. Mu-opioid receptors (MOR) in the striatum...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Ashok, Abhishekh H., Myers, Jim, Reis Marques, Tiago, Rabiner, Eugenii A., Howes, Oliver D.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6776653/
https://ncbi.nlm.nih.gov/pubmed/31582737
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-12366-4
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