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The amylin dyshomeostasis hypothesis: small vessel-type ischemic stroke in the setting of type-2 diabetes mellitus

Recent histological analyses of human brains show that small-vessel type injuries in the setting of type-2 diabetes are colocalized with deposits of amylin, an amyloid-forming hormone secreted by the pancreas. Amylin inclusions are also identified in circulating red blood cells in persons with type-...

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Publicado en:Stroke
Main Authors: Despa, Florin, Goldstein, Larry B.
Formato: Artigo
Idioma:Inglês
Publicado: 2021
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC8154741/
https://ncbi.nlm.nih.gov/pubmed/33947210
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/STROKEAHA.121.034363
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