Causal relationship and shared genetic loci between psoriasis and type 2 diabetes through trans-disease meta-analysis

Psoriasis and type 2 diabetes (T2D) are complex conditions with significant impact on health. Psoriasis patients have higher risk of type 2 diabetes (~1.5 Odds Ratio) and vice versa, controlling for body mass index (BMI), yet there has been limited study comparing their genetic architecture. We hypo...

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Veröffentlicht in:J Invest Dermatol
Hauptverfasser: Patrick, Matthew T, Stuart, Philip E, Zhang, Haihan, Zhao, Qingyuan, Yin, Xianyong, He, Kevin, Zhou, Xu-jie, Mehta, Nehal N., Voorhees, John J, Boehnke, Michael, Gudjonsson, Johann E, Nair, Rajan P, Handelman, Samuel K., Elder, James T, Liu, Dajiang J, Tsoi, Lam C
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2020
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8154633/
https://ncbi.nlm.nih.gov/pubmed/33385400
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jid.2020.11.025
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