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Design, Synthesis, Anticancer Evaluation, Enzymatic Assays, and a Molecular Modeling Study of Novel Pyrazole–Indole Hybrids

[Image: see text] The molecular hybridization concept has recently emerged as a powerful approach in drug discovery. A series of novel indole derivatives linked to the pyrazole moiety were designed and developed via a molecular hybridization protocol as antitumor agents. The target compounds (5a–j a...

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Detalhes bibliográficos
Publicado no:ACS Omega
Main Authors: Hassan, Ashraf S., Moustafa, Gaber O., Awad, Hanem M., Nossier, Eman S., Mady, Mohamed F.
Formato: Artigo
Idioma:Inglês
Publicado em: American Chemical Society 2021
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8154124/
https://ncbi.nlm.nih.gov/pubmed/34056388
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsomega.1c01604
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