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Systemic immunotherapy with micellar resiquimod-polymer conjugates triggers a robust antitumor response in a breast cancer model

Resiquimod is an immunopotent toll-like receptor 7/8 agonist with anti-tumor activity. Despite being potent against skin cancers, it’s poorly tolerated systemically due to toxicity. Integrating resiquimod into nanoparticles presents an avenue to circumvent the toxicity problem. Herein, the preparati...

詳細記述

保存先:
書誌詳細
出版年:Adv Healthc Mater
主要な著者: Kakwere, Hamilton, Zhang, Hua, Ingham, Elizabeth S., Nura-Raie, Marina, Tumbale, Spencer K., Allen, Riley, Tam, Sarah M., Wu, Bo, Liu, Cheng, Kheirolomoom, Azadeh, Fite, Brett Z., Ilovitsh, Asaf, Lewis, Jamal S., Ferrara, Katherine W.
フォーマット: Artigo
言語:Inglês
出版事項: 2021
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC8153207/
https://ncbi.nlm.nih.gov/pubmed/33646600
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/adhm.202100008
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