Reactivity of N-acyl hydrazone probes with the mammalian proteome

Small molecule probes with distinct reactivities are useful tools for the identification and characterization of protein modifications and function. Herein, we show that hydrazone probes with an N-carbamate structural motif react differently from N-carbamates within the human proteome. Mass spectrom...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:RSC Med Chem
Prif Awduron: Shaw, Tyler A., Powdrill, Megan H., Sherratt, Allison R., Garland, Keira, Li, Bin-Jie, Beauchemin, André M., Pezacki, John Paul
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: RSC 2021
Pynciau:
Chemistry
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC8152812/
https://ncbi.nlm.nih.gov/pubmed/34124678
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/d1md00027f
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