Reactivity of N-acyl hydrazone probes with the mammalian proteome

Small molecule probes with distinct reactivities are useful tools for the identification and characterization of protein modifications and function. Herein, we show that hydrazone probes with an N-carbamate structural motif react differently from N-carbamates within the human proteome. Mass spectrom...

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Detalles Bibliográficos
Publicado en:RSC Med Chem
Main Authors: Shaw, Tyler A., Powdrill, Megan H., Sherratt, Allison R., Garland, Keira, Li, Bin-Jie, Beauchemin, André M., Pezacki, John Paul
Formato: Artigo
Idioma:Inglês
Publicado: RSC 2021
Assuntos:
Chemistry
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC8152812/
https://ncbi.nlm.nih.gov/pubmed/34124678
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/d1md00027f
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