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Synthesis and evaluation of bis(imino)anthracene derivatives as G-quadruplex ligands
The synthesis of a small number of bis(imino)anthracene derivatives is reported. They were evaluated via NMR for binding efficacy to the G-quadruplex-forming oligonucleotide sequence (TTGGGTT) and show activity against the HeLa cancer cell line. These novel ligands are compared to previously synthes...
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| Publicado no: | RSC Med Chem |
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| Principais autores: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
RSC
2021
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8152782/ https://ncbi.nlm.nih.gov/pubmed/34124673 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/d0md00428f |
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