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Transcriptome analysis of potential candidate genes and molecular pathways in colitis-associated colorectal cancer of Mkp-1-deficient mice

BACKGROUND: The nuclear phosphatase mitogen-activate protein kinase phosphatase-1 (MKP-1) is a key negative regulator of the innate immune response through the regulation of the biosynthesis of proinflammatory cytokines. In colorectal cancer (CRC), which is induced mainly by chronic inflammation, Mk...

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Publicado en:BMC Cancer
Autores principales: Hammad, Ahmed, Zheng, Zhao-Hong, Namani, Akhileshwar, Elshaer, Mohamed, Wang, Xiu Jun, Tang, Xiuwen
Formato: Artigo
Lenguaje:Inglês
Publicado: BioMed Central 2021
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC8152130/
https://ncbi.nlm.nih.gov/pubmed/34034704
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-021-08200-0
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