Integrated data analysis reveals significant associations of KEAP1 mutations with DNA methylation alterations in lung adenocarcinomas

KEAP1 regulates the cytoprotection induced by NRF2 and has been reported to be a candidate tumor suppressor. Recent evidence has shown that mutations in several driver genes cause aberrant DNA methylation patterns, a hallmark of cancer. However, the correlation between KEAP1 mutations and DNA methyl...

Descripción completa

Guardado en:
Detalles Bibliográficos
Publicado en:Aging (Albany NY)
Autores principales: Elshaer, Mohamed, ElManawy, Ahmed Islam, Hammad, Ahmed, Namani, Akhileshwar, Wang, Xiu Jun, Tang, Xiuwen
Formato: Artigo
Lenguaje:Inglês
Publicado: Impact Journals 2020
Materias:
Research Paper
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7202502/
https://ncbi.nlm.nih.gov/pubmed/32327612
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/aging.103068
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!

Ejemplares similares