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Ultrasensitive tau biosensor cells detect no seeding in Alzheimer’s disease CSF

Tau protein forms self-replicating assemblies (seeds) that may underlie progression of pathology in Alzheimer’s disease (AD) and related tauopathies. Seeding in recombinant protein preparations and brain homogenates has been quantified with “biosensor” cell lines that express tau with a disease-asso...

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Detalhes bibliográficos
Publicado no:Acta Neuropathol Commun
Main Authors: Hitt, Brian D., Vaquer-Alicea, Jaime, Manon, Victor A., Beaver, Joshua D., Kashmer, Omar M., Garcia, Jan N., Diamond, Marc I.
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8152020/
https://ncbi.nlm.nih.gov/pubmed/34039426
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40478-021-01185-8
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