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High Temperature Drives Topoisomerase Mediated Chromosomal Break Repair Pathway Choice
SIMPLE SUMMARY: Targeting topoisomerases has been widely used as anticancer therapeutics. Exposure to high temperature (hyperthermia) protects cells from the cytotoxic effect of topoisomerase-targeting therapeutics, yet the mechanism remains unknown. Here, we report that hyperthermia inhibits the nu...
Tallennettuna:
| Julkaisussa: | Cancers (Basel) |
|---|---|
| Päätekijät: | , , , , , , , |
| Aineistotyyppi: | Artigo |
| Kieli: | Inglês |
| Julkaistu: |
MDPI
2021
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| Aiheet: | |
| Linkit: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8151962/ https://ncbi.nlm.nih.gov/pubmed/34065967 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers13102315 |
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