One and Two-Step In Vitro-In Vivo Correlations Based on USP IV Dynamic Dissolution Applied to Four Sodium Montelukast Products

Montelukast is a weak acid drug characterized by its low solubility in the range of pH 1.2 to 4.5, which may lead to dissolution-limited absorption. The aim of this paper is to develop an in vivo predictive dissolution method for montelukast and to check its performance by establishing a level-A in...

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Bibliografiska uppgifter
I publikationen:Pharmaceutics
Huvudupphovsmän: Prieto-Escolar, Mercedes, Torrado, Juan J., Álvarez, Covadonga, Ruiz-Picazo, Alejandro, Simón-Vázquez, Marta, Govantes, Carlos, Frias, Jesús, García-Arieta, Alfredo, Gonzalez-Alvarez, Isabel, Bermejo, Marival
Materialtyp: Artigo
Språk:Inglês
Publicerad: MDPI 2021
Ämnen:
Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC8151440/
https://ncbi.nlm.nih.gov/pubmed/34064700
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/pharmaceutics13050690
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