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Deregulation of the Interleukin-7 Signaling Pathway in Lymphoid Malignancies
The cytokine interleukin-7 (IL-7) and its receptor are critical for lymphoid cell development. The loss of IL-7 signaling causes severe combined immunodeficiency, whereas gain-of-function alterations in the pathway contribute to malignant transformation of lymphocytes. Binding of IL-7 to the IL-7 re...
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| Publié dans: | Pharmaceuticals (Basel) |
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| Auteurs principaux: | , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
MDPI
2021
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8151260/ https://ncbi.nlm.nih.gov/pubmed/34066732 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ph14050443 |
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