A Monolayer System for the Efficient Generation of Motor Neuron Progenitors and Functional Motor Neurons from Human Pluripotent Stem Cells

Methods for the conversion of human induced pluripotent stem cells (hiPSCs) into motor neurons (MNs) have opened to the generation of patient-derived in vitro systems that can be exploited for MN disease modelling. However, the lack of simplified and consistent protocols and the fact that hiPSC-deri...

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Detalhes bibliográficos
Publicado no:Cells
Main Authors: Cutarelli, Alessandro, Martínez-Rojas, Vladimir A., Tata, Alice, Battistella, Ingrid, Rossi, Daniela, Arosio, Daniele, Musio, Carlo, Conti, Luciano
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2021
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8151197/
https://ncbi.nlm.nih.gov/pubmed/34066970
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cells10051127
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