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Human Motor Neuron Progenitor Transplantation Leads to Endogenous Neuronal Sparing in 3 Models of Motor Neuron Loss

Motor neuron loss is characteristic of many neurodegenerative disorders and results in rapid loss of muscle control, paralysis, and eventual death in severe cases. In order to investigate the neurotrophic effects of a motor neuron lineage graft, we transplanted human embryonic stem cell-derived moto...

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Autors principals: Wyatt, Tanya J., Rossi, Sharyn L., Siegenthaler, Monica M., Frame, Jennifer, Robles, Rockelle, Nistor, Gabriel, Keirstead, Hans S.
Format: Artigo
Idioma:Inglês
Publicat: SAGE-Hindawi Access to Research 2011
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3116523/
https://ncbi.nlm.nih.gov/pubmed/21716648
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4061/2011/207230
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