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Diet-Induced Obesity Impairs Outcomes and Induces Multi-Factorial Deficiencies in Effector T Cell Responses Following Anti-CTLA-4 Combinatorial Immunotherapy in Renal Tumor-Bearing Mice

SIMPLE SUMMARY: Immunotherapy use has become standard for many patients with advanced kidney cancer; unfortunately, <50% of patients experience durable responses. Mounting evidence suggests that modifiable factors, such as diet and obesity, impact immunotherapy outcomes. Obesity, a major U.S. hea...

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Bibliografiska uppgifter
I publikationen:Cancers (Basel)
Huvudupphovsmän: Turbitt, William J., Boi, Shannon K., Gibson, Justin T., Orlandella, Rachael M., Norian, Lyse A.
Materialtyp: Artigo
Språk:Inglês
Publicerad: MDPI 2021
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC8151089/
https://ncbi.nlm.nih.gov/pubmed/34064933
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers13102295
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