In vitro Characterization of the Regional Binding Distribution of Amyloid PET Tracer Florbetaben and the Glia Tracers Deprenyl and PK11195 in Autopsy Alzheimer’s Brain Tissue

BACKGROUND: Emerging evidence indicates a central role of gliosis in Alzheimer’s disease (AD) pathophysiology. However, the regional distribution and interaction of astrogliosis and microgliosis in association with amyloid-β (Aβ) still remain uncertain. OBJECTIVE: Here we studied the pathological pr...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:J Alzheimers Dis
Main Authors: Ni, Ruiqing, Röjdner, Jennie, Voytenko, Larysa, Dyrks, Thomas, Thiele, Andrea, Marutle, Amelia, Nordberg, Agneta
Format: Artigo
Jezik:Inglês
Izdano: IOS Press 2021
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC8150513/
https://ncbi.nlm.nih.gov/pubmed/33749648
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3233/JAD-201344
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