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[(11)C]-(R)PK11195 tracer kinetics in the brain of glioma patients and a comparison of two referencing approaches

PURPOSE: Translocator protein (TSPO) is a biomarker of neuroinflammation that can be imaged by PET using [(11)C]-(R)PK11195. We sought to characterize the [(11)C]-(R)PK11195 kinetics in gliomas of different histotypes and grades, and to compare two reference tissue input functions (supervised cluste...

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Main Authors: Su, Zhangjie, Herholz, Karl, Gerhard, Alexander, Roncaroli, Federico, Du Plessis, Daniel, Jackson, Alan, Turkheimer, Federico, Hinz, Rainer
Format: Artigo
Jezik:Inglês
Izdano: Springer Berlin Heidelberg 2013
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3738844/
https://ncbi.nlm.nih.gov/pubmed/23715902
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00259-013-2447-2
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