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Hexarelin Modulation of MAPK and PI3K/Akt Pathways in Neuro-2A Cells Inhibits Hydrogen Peroxide—Induced Apoptotic Toxicity

Hexarelin, a synthetic hexapeptide, exerts cyto-protective effects at the mitochondrial level in cardiac and skeletal muscles, both in vitro and in vivo, may also have important neuroprotective bioactivities. This study examined the inhibitory effects of hexarelin on hydrogen peroxide (H(2)O(2))-ind...

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Détails bibliographiques
Publié dans:Pharmaceuticals (Basel)
Auteurs principaux: Meanti, Ramona, Rizzi, Laura, Bresciani, Elena, Molteni, Laura, Locatelli, Vittorio, Coco, Silvia, Omeljaniuk, Robert John, Torsello, Antonio
Format: Artigo
Langue:Inglês
Publié: MDPI 2021
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC8150489/
https://ncbi.nlm.nih.gov/pubmed/34066741
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ph14050444
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