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Complete deconvolution of DNA methylation signals from complex tissues: a geometric approach

MOTIVATION: It is a common practice in epigenetics research to profile DNA methylation on tissue samples, which is usually a mixture of different cell types. To properly account for the mixture, estimating cell compositions has been recognized as an important first step. Many methods were developed...

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Publicado en:Bioinformatics
Main Authors: Zhang, Weiwei, Wu, Hao, Li, Ziyi
Formato: Artigo
Idioma:Inglês
Publicado: Oxford University Press 2020
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC8150138/
https://ncbi.nlm.nih.gov/pubmed/33135072
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btaa930
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