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Pharmacological Modulators of Small GTPases of Rho Family in Neurodegenerative Diseases

Classical Rho GTPases, including RhoA, Rac1, and Cdc42, are members of the Ras small GTPase superfamily and play essential roles in a variety of cellular functions. Rho GTPase signaling can be turned on and off by specific GEFs and GAPs, respectively. These features empower Rho GTPases and their ups...

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Detalhes bibliográficos
Publicado no:Front Cell Neurosci
Main Authors: Guiler, William, Koehler, Addison, Boykin, Christi, Lu, Qun
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8149604/
https://ncbi.nlm.nih.gov/pubmed/34054432
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fncel.2021.661612
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