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What combines best with GLP-1 for obesity treatment: GIP receptor agonists or antagonists?
Lu et al.(1) previously demonstrated that antagonist antibodies against the GIP receptor promote weight loss combined with GLP-1. They now elegantly developed a conjugate of GIPR antibodies and GLP-1 and show effective weight loss in obese non-human primates.
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| Publié dans: | Cell Rep Med |
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| Auteur principal: | |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Elsevier
2021
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8149460/ https://ncbi.nlm.nih.gov/pubmed/34095885 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.xcrm.2021.100284 |
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