A Gender-Dependent Molecular Switch of Inflammation via MyD88/Estrogen Receptor-Alpha Interaction

INTRODUCTION: Most Toll-like receptors and IL-1/IL-18 receptors activate a signaling cascade via the adaptor molecule MyD88, resulting in NF-κB activation and inflammatory cytokine and chemokine production. Females are less susceptible than males to inflammatory conditions, presumably due to protect...

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Bibliografiske detaljer
Udgivet i:J Inflamm Res
Main Authors: El Sabeh, Rana, Bonnet, Mélanie, Le Corf, Katy, Lang, Kevin, Kfoury, Alain, Badran, Bassam, Hussein, Nader, Virard, Francois, Treilleux, Isabelle, Le Romancer, Muriel, Lebecque, Serge, Manie, Serge, Coste, Isabelle, Renno, Toufic
Format: Artigo
Sprog:Inglês
Udgivet: Dove 2021
Fag:
Original Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8149287/
https://ncbi.nlm.nih.gov/pubmed/34045885
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/JIR.S306805
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