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An intramolecular catalytic hairpin assembly on a DNA tetrahedron for mRNA imaging in living cells: improving reaction kinetics and signal stability

Enzyme-free amplification techniques based on dynamic DNA self-assembly (DDSA) have recently been developed for the in situ detection of mRNA in living cells. However, signal generation in traditional DDSA amplifiers is mainly dependent on the random diffusion of dissociative probes in a bulk soluti...

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Bibliografiske detaljer
Udgivet i:Chem Sci
Main Authors: Qing, Zhihe, Hu, Jinlei, Xu, Jingyuan, Zou, Zhen, Lei, Yanli, Qing, Taiping, Yang, Ronghua
Format: Artigo
Sprog:Inglês
Udgivet: The Royal Society of Chemistry 2019
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8148388/
https://ncbi.nlm.nih.gov/pubmed/34123293
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c9sc04916a
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