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Metabolic inhibitors of bacterial glycan biosynthesis

The bacterial cell wall is a quintessential drug target due to its critical role in colonization of the host, pathogen survival, and immune evasion. The dense cell wall glycocalyx contains distinctive monosaccharides that are absent from human cells, and proper assembly of monosaccharides into highe...

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Publicat a:Chem Sci
Autors principals: Williams, Daniel A., Pradhan, Kabita, Paul, Ankita, Olin, Ilana R., Tuck, Owen T., Moulton, Karen D., Kulkarni, Suvarn S., Dube, Danielle H.
Format: Artigo
Idioma:Inglês
Publicat: The Royal Society of Chemistry 2020
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC8148367/
https://ncbi.nlm.nih.gov/pubmed/34123271
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c9sc05955e
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