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Metabolic inhibitors of bacterial glycan biosynthesis

The bacterial cell wall is a quintessential drug target due to its critical role in colonization of the host, pathogen survival, and immune evasion. The dense cell wall glycocalyx contains distinctive monosaccharides that are absent from human cells, and proper assembly of monosaccharides into highe...

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Detalhes bibliográficos
Publicado no:Chem Sci
Main Authors: Williams, Daniel A., Pradhan, Kabita, Paul, Ankita, Olin, Ilana R., Tuck, Owen T., Moulton, Karen D., Kulkarni, Suvarn S., Dube, Danielle H.
Formato: Artigo
Idioma:Inglês
Publicado em: The Royal Society of Chemistry 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8148367/
https://ncbi.nlm.nih.gov/pubmed/34123271
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c9sc05955e
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