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A trimeric capable gB CMV vaccine provides limited protection against a highly cell associated and epithelial tropic strain of cytomegalovirus in guinea pigs

Multiple strains of human cytomegalovirus (HCMV) can cause congenital cytomegalovirus (cCMV) by primary or secondary infection. The viral gB glycoprotein is a leading vaccine candidate, essential for infection of all cell-types, and immunodominant antibody target. Guinea pig cytomegalovirus (GPCMV)...

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Détails bibliographiques
Publié dans:J Gen Virol
Auteurs principaux: Choi, K. Yeon, El-Hamdi, Nadia S., McGregor, Alistair
Format: Artigo
Langue:Inglês
Publié: Microbiology Society 2021
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC8148303/
https://ncbi.nlm.nih.gov/pubmed/33729125
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1099/jgv.0.001579
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