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A trimeric capable gB CMV vaccine provides limited protection against a highly cell associated and epithelial tropic strain of cytomegalovirus in guinea pigs

Multiple strains of human cytomegalovirus (HCMV) can cause congenital cytomegalovirus (cCMV) by primary or secondary infection. The viral gB glycoprotein is a leading vaccine candidate, essential for infection of all cell-types, and immunodominant antibody target. Guinea pig cytomegalovirus (GPCMV)...

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Detalhes bibliográficos
Publicado no:J Gen Virol
Main Authors: Choi, K. Yeon, El-Hamdi, Nadia S., McGregor, Alistair
Formato: Artigo
Idioma:Inglês
Publicado em: Microbiology Society 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8148303/
https://ncbi.nlm.nih.gov/pubmed/33729125
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1099/jgv.0.001579
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