Effects of Sponge-Derived Alkaloids on Activities of the Bacterial α-D-Galactosidase and Human Cancer Cell α-N-Acetylgalactosaminidase

During a search for glycosidase inhibitors among marine natural products, we applied an integrated in vitro and in silico approach to evaluate the potency of some aaptamines and makaluvamines isolated from marine sponges on the hydrolyzing activity of α-N-acetylgalactosaminidase (α-NaGalase) from hu...

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Bibliographische Detailangaben
Veröffentlicht in:Biomedicines
Hauptverfasser: Utkina, Natalia, Likhatskaya, Galina, Malyarenko, Olesya, Ermakova, Svetlana, Balabanova, Larisa, Slepchenko, Lubov, Bakunina, Irina
Format: Artigo
Sprache:Inglês
Veröffentlicht: MDPI 2021
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8147984/
https://ncbi.nlm.nih.gov/pubmed/34063022
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/biomedicines9050510
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