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Effects of Sponge-Derived Alkaloids on Activities of the Bacterial α-D-Galactosidase and Human Cancer Cell α-N-Acetylgalactosaminidase

During a search for glycosidase inhibitors among marine natural products, we applied an integrated in vitro and in silico approach to evaluate the potency of some aaptamines and makaluvamines isolated from marine sponges on the hydrolyzing activity of α-N-acetylgalactosaminidase (α-NaGalase) from hu...

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Detalles Bibliográficos
Publicado en:Biomedicines
Main Authors: Utkina, Natalia, Likhatskaya, Galina, Malyarenko, Olesya, Ermakova, Svetlana, Balabanova, Larisa, Slepchenko, Lubov, Bakunina, Irina
Formato: Artigo
Idioma:Inglês
Publicado: MDPI 2021
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC8147984/
https://ncbi.nlm.nih.gov/pubmed/34063022
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/biomedicines9050510
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