Construction and Immunogenicity of Modified mRNA-Vaccine Variants Encoding Influenza Virus Antigens

Nucleic acid-based influenza vaccines are a promising platform that have recently and rapidly developed. We previously demonstrated the immunogenicity of DNA vaccines encoding artificial immunogens AgH1, AgH3, and AgM2, which contained conserved fragments of the hemagglutinin stem of two subtypes of...

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Publicat a:Vaccines (Basel)
Autors principals: Starostina, Ekaterina V., Sharabrin, Sergei V., Antropov, Denis N., Stepanov, Grigory A., Shevelev, Georgiy Yu., Lemza, Anna E., Rudometov, Andrey P., Borgoyakova, Mariya B., Rudometova, Nadezhda B., Marchenko, Vasiliy Yu., Danilchenko, Natalia V., Chikaev, Anton N., Bazhan, Sergei I., Ilyichev, Alexander A., Karpenko, Larisa I.
Format: Artigo
Idioma:Inglês
Publicat: MDPI 2021
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC8147809/
https://ncbi.nlm.nih.gov/pubmed/34063689
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/vaccines9050452
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