Hard wiring of normal tissue-specific chromosome-wide gene expression levels is an additional factor driving cancer type-specific aneuploidies

BACKGROUND: Many carcinomas have recurrent chromosomal aneuploidies specific to the tissue of tumor origin. The reason for this specificity is not completely understood. METHODS: In this study, we looked at the frequency of chromosomal arm gains and losses in different cancer types from the The Canc...

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Publicat a:Genome Med
Autors principals: Patkar, Sushant, Heselmeyer-Haddad, Kerstin, Auslander, Noam, Hirsch, Daniela, Camps, Jordi, Bronder, Daniel, Brown, Markus, Chen, Wei-Dong, Lokanga, Rachel, Wangsa, Darawalee, Wangsa, Danny, Hu, Yue, Lischka, Annette, Braun, Rüdiger, Emons, Georg, Ghadimi, B. Michael, Gaedcke, Jochen, Grade, Marian, Montagna, Cristina, Lazebnik, Yuri, Difilippantonio, Michael J., Habermann, Jens K., Auer, Gert, Ruppin, Eytan, Ried, Thomas
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2021
Matèries:
Research
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC8147418/
https://ncbi.nlm.nih.gov/pubmed/34034815
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13073-021-00905-y
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