Effect of Dihydroartemisinin-Piperaquine on the Pharmacokinetics of Praziquantel for Treatment of Schistosoma mansoni Infection

Praziquantel (PZQ) and dihydroartemisinin-piperaquine (DHP) combination recently showed superior effectiveness than PZQ alone to treat intestinal schistosomiasis. In this follow-up study, we investigated the effect of DHP co-administration on the pharmacokinetics of PZQ and its enantiomers among 64...

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Detalhes bibliográficos
Publicado no:Pharmaceuticals (Basel)
Main Authors: Minzi, Omary Mashiku, Mnkugwe, Rajabu Hussein, Ngaimisi, Eliford, Kinung’hi, Safari, Hansson, Anna, Pohanka, Anton, Kamuhabwa, Appolinary, Aklillu, Eleni
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2021
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8145331/
https://ncbi.nlm.nih.gov/pubmed/33922522
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ph14050400
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