Safety and Pharmacokinetics of a Tenofovir Alafenamide Fumarate-Emtricitabine based Oral Antiretroviral Regimen for Prevention of HIV Acquisition in Women: A Randomized Controlled Trial

BACKGROUND: Daily oral emtricitabine (FTC, F)/tenofovir disoproxil fumarate (TDF) combination is approved for HIV pre-exposure prophylaxis (PrEP) in men and women. Tenofovir alafenamide fumarate (TAF) is a newer, more potent prodrug of tenofovir (TFV), and in combination with FTC, has recently been...

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Vydáno v:EClinicalMedicine
Hlavní autoři: Thurman, Andrea R., Schwartz, Jill L., Cottrell, Mackenzie L., Brache, Vivian, Chen, Beatrice A., Cochón, Leila, Ju, Susan, McGowan, Ian, Rooney, James F., McCallister, Scott, Doncel, Gustavo F.
Médium: Artigo
Jazyk:Inglês
Vydáno: Elsevier 2021
Témata:
Research paper
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC8144741/
https://ncbi.nlm.nih.gov/pubmed/34041459
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.eclinm.2021.100893
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