Down-Regulating the Expression of miRNA-21 Inhibits the Glucose Metabolism of A549/DDP Cells and Promotes Cell Death Through the PI3K/AKT/mTOR/HIF-1α Pathway

miRNA-21 is a single-stranded non-coding RNA that is highly expressed in a variety of tumor cells. It participates in tumor cell proliferation, metabolism, metastasis, and drug resistance. Here, we tested the potential mechanism of miRNA-21 in cisplatin-resistant non-small cell lung cancer A549/DDP...

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Detalhes bibliográficos
Publicado no:Front Oncol
Main Authors: Sun, Ye, Liu, Wenjun, Zhao, Qiuyu, Zhang, Ruiqi, Wang, Jianbo, Pan, Pengyu, Shang, Hai, Liu, Chunying, Wang, Chun
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2021
Assuntos:
Oncology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8144645/
https://ncbi.nlm.nih.gov/pubmed/34046349
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fonc.2021.653596
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