Shenmai Injection Supresses Glycolysis and Enhances Cisplatin Cytotoxicity in Cisplatin-Resistant A549/DDP Cells via the AKT-mTOR-c-Myc Signaling Pathway

Tumor cells, especially drug-resistant cells, predominately support growth by glycolysis even under the condition of adequate oxygen, which is known as the Warburg effect. Glucose metabolism reprogramming is one of the main factors causing tumor resistance. Previous studies on Shenmai injection (SMI...

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Detalhes bibliográficos
Publicado no:Biomed Res Int
Main Authors: Sun, Ye, Chen, Yushi, Xu, Ming, Liu, Chunying, Shang, Hai, Wang, Chun
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi 2020
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7327568/
https://ncbi.nlm.nih.gov/pubmed/32685545
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2020/9243681
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