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Engineering supramolecular organizing centers for optogenetic control of innate immune responses

The spatiotemporal organization of oligomeric protein complexes and translocons, such as the supramolecular organizing centers (SMOC) made of MyDDosome and MAVSome, are essential for transcriptional activation of host inflammatory responses and immune metabolisms. Light-inducible assembly of MyDDoso...

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Bibliographic Details
Published in:Adv Biol (Weinh)
Main Authors: Tan, Peng, He, Lian, Zhou, Yubin
Format: Artigo
Language:Inglês
Published: 2020
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC8144545/
https://ncbi.nlm.nih.gov/pubmed/34028210
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/adbi.202000147
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