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Engineering supramolecular organizing centers for optogenetic control of innate immune responses

The spatiotemporal organization of oligomeric protein complexes and translocons, such as the supramolecular organizing centers (SMOC) made of MyDDosome and MAVSome, are essential for transcriptional activation of host inflammatory responses and immune metabolisms. Light-inducible assembly of MyDDoso...

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Detalhes bibliográficos
Publicado no:Adv Biol (Weinh)
Main Authors: Tan, Peng, He, Lian, Zhou, Yubin
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8144545/
https://ncbi.nlm.nih.gov/pubmed/34028210
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/adbi.202000147
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