Tolerability and age‐dependent toxicokinetics following perinatal hydroxyurea treatment in Sprague Dawley rats

Hydroxyurea (HU) is a valuable therapy for individuals with sickle cell anemia. With increased use of HU in children and throughout their lives, it is important to understand the potential effects of HU therapy on their development and fertility. Thus, studies were conducted to identify appropriate...

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Detalhes bibliográficos
Publicado no:J Appl Toxicol
Main Authors: Huang, Madelyn C., Turner, Katie J., Vallant, Molly, Robinson, Veronica G., Lu, Yi, Price, Catherine J., Fennell, Timothy R., Silinski, Melanie A., Waidyanatha, Suramya, Ryan, Kristen R., Black, Sherry R., Fernando, Reshan A., McIntyre, Barry S.
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2020
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8144245/
https://ncbi.nlm.nih.gov/pubmed/33241551
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jat.4087
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