Disposition and metabolism of N-butylbenzenesulfonamide in Sprague Dawley rats and B6C3F1/N mice and in vitro in hepatocytes from rats, mice, and humans

N-Butylbenzenesulfonamide (NBBS) is a plasticizer detected in the environment suggesting potential human exposure. These studies investigated the in vitro hepatic clearance and disposition of [(14)C]NBBS in rodents following a single gavage (2, 20 or 200 mg/kg) or intravenous (IV) administration (20...

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Pubblicato in:Toxicol Lett
Autori principali: Waidyanatha, Suramya, Black, Sherry R., Patel, Purvi R., Rider, Cynthia V., Watson, Scott L., Snyder, Rodney W., Fennell, Timothy R.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2019
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7028346/
https://ncbi.nlm.nih.gov/pubmed/31760063
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.toxlet.2019.11.015
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