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Sensitivity, specificity, and accuracy of a liquid biopsy approach utilizing molecular amplification pools

Circulating cell-free DNA (cfDNA) has the potential to be a specific biomarker for the therapeutic management of lung cancer patients. Here, a new sequencing error-reduction method based on molecular amplification pools (MAPs) was utilized to analyze cfDNA in lung cancer patients. We determined the...

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Dettagli Bibliografici
Pubblicato in:Sci Rep
Autori principali: Garcia, Jessica, Kamps-Hughes, Nick, Geiguer, Florence, Couraud, Sébastien, Sarver, Brice, Payen, Léa, Ionescu-Zanetti, Cristian
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group UK 2021
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC8144209/
https://ncbi.nlm.nih.gov/pubmed/34031447
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-021-89592-8
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