Cargando...

PKC-phosphorylation of Liprin-α3 triggers phase separation and controls presynaptic active zone structure

The active zone of a presynaptic nerve terminal defines sites for neurotransmitter release. Its protein machinery may be organized through liquid–liquid phase separation, a mechanism for the formation of membrane-less subcellular compartments. Here, we show that the active zone protein Liprin-α3 rap...

Descrición completa

Gardado en:
Detalles Bibliográficos
Publicado en:Nat Commun
Main Authors: Emperador-Melero, Javier, Wong, Man Yan, Wang, Shan Shan H., de Nola, Giovanni, Nyitrai, Hajnalka, Kirchhausen, Tom, Kaeser, Pascal S.
Formato: Artigo
Idioma:Inglês
Publicado: Nature Publishing Group UK 2021
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC8144191/
https://ncbi.nlm.nih.gov/pubmed/34031393
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-021-23116-w
Tags: Engadir etiqueta
Sen Etiquetas, Sexa o primeiro en etiquetar este rexistro!