Thymoquinone Is a Multitarget Single Epidrug That Inhibits the UHRF1 Protein Complex

Silencing of tumor suppressor genes (TSGs) through epigenetic mechanisms, mainly via abnormal promoter DNA methylation, is considered a main mechanism of tumorigenesis. The abnormal DNA methylation profiles are transmitted from the cancer mother cell to the daughter cells through the involvement of...

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Bibliografske podrobnosti
izdano v:Genes (Basel)
Main Authors: Abdullah, Omeima, Omran, Ziad, Hosawi, Salman, Hamiche, Ali, Bronner, Christian, Alhosin, Mahmoud
Format: Artigo
Jezik:Inglês
Izdano: MDPI 2021
Teme:
Review
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC8143546/
https://ncbi.nlm.nih.gov/pubmed/33922029
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/genes12050622
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