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Signalling pathways in UHRF1-dependent regulation of tumor suppressor genes in cancer
Epigenetic silencing of tumor suppressor genes (TSGs) through DNA methylation and histone changes is a main hallmark of cancer. Ubiquitin-like with PHD and RING Finger domains 1 (UHRF1) is a potent oncogene overexpressed in various solid and haematological tumors and its high expression levels are a...
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| Publicado no: | J Exp Clin Cancer Res |
|---|---|
| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5108085/ https://ncbi.nlm.nih.gov/pubmed/27839516 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13046-016-0453-5 |
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