Signalling pathways in UHRF1-dependent regulation of tumor suppressor genes in cancer

Epigenetic silencing of tumor suppressor genes (TSGs) through DNA methylation and histone changes is a main hallmark of cancer. Ubiquitin-like with PHD and RING Finger domains 1 (UHRF1) is a potent oncogene overexpressed in various solid and haematological tumors and its high expression levels are a...

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發表在:J Exp Clin Cancer Res
Main Authors: Alhosin, Mahmoud, Omran, Ziad, Zamzami, Mazin A., Al-Malki, Abdulrahman L., Choudhry, Hani, Mousli, Marc, Bronner, Christian
格式: Artigo
語言:Inglês
出版: BioMed Central 2016
主題:
Review
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC5108085/
https://ncbi.nlm.nih.gov/pubmed/27839516
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13046-016-0453-5
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